Deeplex® HelP
Innovative Diagnostic Solution
for Helicobacter pylori infections
Powered by GenoScreen
Become an early user and be among the first to try out the kit.
The cutting-edge solution for Helicobacter pylori
6
antibiotics
screened
7
targets for strain type identification
2
targets for virulence prediction
48h
from clinical samples to results
Deeplex HelP
includes
- Deeplex Master Mix: single PCR mix for amplification of Helicobacter pylori drug resistance-associated gene targets combined with targets for species identification and virulence prediction.
- Internal control for in-sample quality control.
- Positive control for test validation.
- Automated analysis via GenoScreen proprietary secure pipeline.
Download
the technical note
Helicobacter pylori, a global threat
Helicobacter pylori infection is a global health issue, causing stomach diseases such as gastritis, peptic ulcers and cancer. This bacterium affects about 50% of the world’s population, with varying prevalence across geographical regions. The risk of developing diseases associated with H. pylori depends on multiple factors but global health authorities estimate that, of the people infected worldwide, 660 million people (15%) will develop peptic ulcers and 66 million (1.5%) will develop stomach cancer.
Antibiotic resistance is the major cause of H. pylori treatment failures and the WHO classifies H. pylori as a priority antibiotic-resistant pathogen. To overcome this challenge, established guidelines recommend that H. pylori treatment be guided by the local antibiotic resistance prevalence. Deeplex HelP is a powerful tool to easily test for antibiotic resistance allowing the selection of optimal treatment regimens minimising the emergence of resistance.
Prevent gastric inflammation and ulceries
The pathogenicity and treatability of H. pylori are dependent on a complex interplay between various factors, among which bacterial characteristics such as strain identity, strain virulence and antibiotic resistance.
Traditional methods (PCR, LPA…) are unable to accurately detect all these factors. Moreover H. pylori culture is time-consuming, fastidious and costly. With Deeplex HelP, clinicians can have access to H. pylori strain identity, virulence and antibiotic resistance without the need for culture and in a single assay, facilitating guided therapy thus reducing the risk of treatment failure and preventing complications such as gastric cancer.
